梅一德,男,毕业于中国科学技术大学,博士,
中国科学技术大学教授、博士生导师。
人物经历
1996年至2000年毕业于
安徽大学生命科学学院,获
理学学士学位;
2002年至2007年,就读于
中国科学技术大学生命科学学院,并获博士学位。
2007年至2011年于
宾夕法尼亚大学医学院从事博士后研究。
研究方向
1、癌蛋白和抑癌蛋白介导的信号通路以及其在肿瘤形成中的作用
2、非编码RNA与肿瘤形成
论文专著
(1) Long non-coding RNA EMS connects c-Myc to cell cycle control and tumorigenesis - Proc Natl Acad Sci U S A - 2019 -
(2) RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III-dependent transcription - Journal of Biological Chemistry - 2019 -
(3) Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7 - EMBO Reports - 2018 -
(4) TRMP, a p53-inducible long noncoding RNA, regulates G1/S cell cycle progression by modulating IRES-dependent p27 translation - Cell Death & Disease - 2018 -
(5) Mitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling - Nature Communications - 2015 -
(6) Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect.(SCI) - Molecular Cell - 2014 -
(7) Role of tumor necrosis factor alpha-induced protein 1 in paclitaxel resistance.(SCI) - Oncogene - 2014 -
(8) Siva1 inhibits p53 function by acting as an E3 ubiquitin ligase of ARF.(SCI) - Nature Communications - 2013 -
(9) XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling.(SCI) - EMBO Journal - 2013 -
(10) Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression - Cell Death Dis - 2013 -
(11) p53-Facilitated miR-199a-3p regulates somatic cell reprogramming.(SCI) - Stem Cells - 2012 -
(12) tRNA binds to cytochrome c and inhibits caspase activation.(SCI) - Molecular Cell - 2010 -