性别:男
人物经历
学习经历
1984.9—1989.6
中国科技大学生物系生物物理学专业,获学士学位。
1989.9—1994.6中国科学院上海生理所(今中国科学院神经科学研究所)神经生物学专业,获博士学位(导师李朝义院士)。
1994.8-1996.6,美国加州大学伯克利分校,博士后(合作导师:Prof Gerald Westheimer)。
工作经历
1996.7-1999.5年,德国马克思普朗克学会生物控制论研究所,访问学者。
1999.6-2007.6,美国洛克菲勒大学,研究助理教授(合作导师:Charles Gilbert 院士)。
2007.3-,北京师范大学认知神经科学与学习国家重点实验室,主任、教授、博士生导师。
现任职务:
新世纪百千万人才工程国家级人选。
研究方向
视知觉的神经机制。
主要贡献
学术成果
通过在猕猴大脑皮层中植入
微电极阵列,研究猴子在执行各种
视觉检测和分辨任务时神经元的反应特性,探讨视知觉的神经机制。主要研究兴趣在于视觉及其皮层加工过程的自适应性,包括各种动态特性和可塑性,着重研究以下问题:(1)视皮层神经元如何根据特定的图形上下文,动态地对各种图象信息进行整合和分割,从而形成知觉表象上的图形和背景;(2)选择性注意等高级认知功能如何动态地调节视觉神经元的反应特性,从而最为有效地处理视觉图象中与行为密切相关的信息;(3)过去的经验如何影响视觉神经元对刺激的编码以及知觉学习的神经机制,即知觉训练过程中所产生的内隐记忆是如何被存储和提取的。
发表论文
Journal Papers
Gilbert, C.D., and Li, W. (2013). Top-down influences on visual processing. Nat. Rev. Neurosci. 14, 350-363.
McFarland, R., Roebuck, H., Yan, Y., Majolo, B., Li, W., and Guo, K. (2013). Social interactions through the eyes of macaques and humans. PLos One 8, e56437.
Ramalingam, N., McManus, J.N.J., Li, W., and Gilbert, C.D. (2013). Top-down modulation of lateral interactions in visual cortex. J. Neurosci. 33, 1773-1789.
Gilbert, C.D., and Li, W. (2012). Adult visual cortical plasticity. Neuron 75, 250-264.
Xing, D., Shen, Y., Burns, S., Yeh, C.-I., Shapley, R., and Li, W. (2012). Stochastic generation of gamma-band activity in primary visual cortex of awake and anesthetized monkeys. J. Neurosci. 32.
Pan, Y., Chen, M., Yin, J., An, X., Zhang, X., Lu, Y., Gong, H., Li, W., and Wang, W. (2012). Equivalent representation of real and illusory contours in macaque V4. J. Neurosci. 32, 6760-6770.
McManus, J.N.J., Li, W., and Gilbert, C.D. (2011). Adaptive shape processing in primary visual cortex. Proc. Natl. Acad. Sci. U. S. A. 108, 9739-9746.
Zhang, E., and Li, W. (2010). Perceptual learning beyond retinotopic reference frame. Proc. Natl. Acad. Sci. U. S. A. 107.
Gilbert, C.D., Li, W., and Piech, V. (2009). Perceptual learning and adult cortical plasticity. J. Physiol. (Lond). 587, 2743-2751.
Li, W., Piech, V., and Gilbert, C.D. (2008). Learning to link visual contours. Neuron 57, 442-451.
Li, W., Piech, V., and Gilbert, C.D. (2006). Contour saliency in primary visual cortex. Neuron 50, 951-962.
Stettler, D.D., Yamahachi, H., Li, W., Denk, W., and Gilbert, C.D. (2006). Axons and synaptic boutons are highly dynamic in adult visual cortex. Neuron 49, 877-887.
Li, W., Piech, V., and Gilbert, C.D. (2004). Perceptual learning and top-down influences in primary visual cortex. Nat. Neurosci. 7, 651-657.
Li, W., and Gilbert, C.D. (2002). Global contour saliency and local colinear interactions. J. Neurophysiol. 88, 2846-2856.
Crist, R.E., Li, W., and Gilbert, C.D. (2001). Learning to see: experience and attention in primary visual cortex. Nat. Neurosci. 4, 519-525.
Li, W., Thier, P., and Wehrhahn, C. (2001). Neuronal responses from beyond the classic receptive field in V1 of alert monkeys. Exp. Brain Res. 139, 359-371.
Li, W., Thier, P., and Wehrhahn, C. (2000). Contextual influence on orientation discrimination of humans and responses of neurons in V1 of alert monkeys. J. Neurophysiol. 83, 941-954.
Li, W., and Westheimer, G. (1997). Human discrimination of the implicit orientation of simple symmetrical patterns. Vision Res. 37, 565-572.
Westheimer, G., and Li, W. (1997). Classifying illusory contours: Edges defined by ''pacman'' and monocular tokens. J. Neurophysiol. 77, 731-736.
Westheimer, G., and Li, W. (1996). Classifying illusory contours by means of orientation discrimination. J. Neurophysiol. 75, 523-537.
Wehrhahn, C., Li, W., and Westheimer, G. (1996). Patterns that impair discrimination of line orientation in human vision. Perception 25, 1053-1064.
Li, C.Y., and Li, W. (1994). Extensive integration field beyond the classical receptive field of cat's striate cortical neurons-classification and tuning properties. Vision Res. 34, 2337-2355.
Book Chapters
Li, W., and Gilbert, C.D. (2009). Visual cortical plasticity and perceptual learning. In The cognitive neurosciences, M.S. Gazzaniga, ed. (Cambridge, Massachusetts: The MIT Press), pp. 129-140.
Li, W., and Gilbert, C.D. (2008). Perceptual Learning: neural mechanisms. In Encyclopedia of Neuroscience, L.R. Squire, ed. (Oxford: Academic Press), pp. 535-541.
Li, W., and Gilbert, C.D. (2007). Perceptual learning. In The Senses: A comprehensive reference, A.I. Basbaum et al., eds. (New York: Academic Press), pp. 303-328.
Li, C.Y., and Li, W. (1994). Extensive integration field beyond the classical receptive field of cat's striate cortical neurons-classification and tuning properties. Vision Res.
34, 2337-2355.编写专著
Li, W., and Gilbert, C.D. (2009). Visual cortical plasticity and perceptual learning. In The cognitive neurosciences, M.S. Gazzaniga, ed. (Cambridge, Massachusetts: The MIT Press), pp. 129-140.
Li, W., and Gilbert, C.D. (2008). Perceptual Learning: neural mechanisms. In Encyclopedia of Neuroscience, L.R. Squire, ed. (Oxford: Academic Press), pp. 535-541.
Li, W., and Gilbert, C.D. (2007). Perceptual learning. In The Senses: A comprehensive reference, A.I. Basbaum et al., eds. (New York: Academic Press), pp. 303-328.
Li, W., and Gilbert, C.D. (2009). Visual cortical plasticity and perceptual learning. In The cognitive neurosciences, M.S. Gazzaniga, ed. (Cambridge, Massachusetts: The MIT Press), pp. 129-140.
Li, W., and Gilbert, C.D. (2008). Perceptual Learning: neural mechanisms. In Encyclopedia of Neuroscience, L.R. Squire, ed. (Oxford: Academic Press), pp. 535-541.
Li, W., and Gilbert, C.D. (2007). Perceptual learning. In The Senses: A comprehensive reference, A.I. Basbaum et al., eds. (New York: Academic Press), pp. 303-328.