尹宗宁
四川大学华西药学院药剂教研室教授
尹宗宁,女,博士,四川大学华西药学院药剂教研室教授,博士生导师,四川省药学会药剂学专业委员会委员, 四川省新药审评专家。
人物经历
1981-1986 华西医科大学药学院药学专业本科
1990-1993 华西医科大学药学院药剂学硕士研究生
1995-1998 华西医科大学药学院药剂学博士研究生
1986-1990 四川抗菌素工业研究所任助理研究员
1993- 华西医科大学药学院、四川大学华西药学院任讲师、副教授、教授
社会职务
中国颗粒学会生物颗粒专委会委员,四川省药学会药剂学专业委员会副主任委员,四川省新药审评专家,国家科技部、教育部、发改委、浙江省、广东省、北京市、成都市、重庆市科技评审专家。《Asian Journal of Pharmaceutics Sciences》杂志编委。
研究方向
1.药物新剂型及缓控释制剂的研究
2.多肽与蛋白类药物制剂及靶向给药系统的研究
3.蛋白制剂稳定性的研究
研究课题
1.国家自然科学基金项目,基于蛋白质聚集体指标调控的蛋白质溶液稳定性研究,项目批准号81673363,负责人, 2017.1-2020.12。
2.国家自然科学基金项目,基于物质结构设计的蛋白药物自乳化复乳给药系统的构建及形成机理研究,项目批准号81373338,负责人, 2014.1-2017.12。
3.国家自然科学基金项目,蛋白质药物溶液稳定性的试验方法与理论基础,项目批准号30973659,负责人, 2010.1-2012.12。
4.国家自然科学基金项目,受体介导抗血管栓塞给药系统的研究,批准号:30371696。负责人,2004-2006。
5.教育部回国基金,溶液型蛋白质药物制剂稳定性试验方法,项目编号:201069-5-4 ,负责人,2010.1-2012.12。
6.四川省科技支撑计划,雷替曲塞结肠靶向定位给药体统的应用研究,项目编号:2010SZ0093,负责人, 2010,1-2012.12。
7.企业合作项目
代表论文
1.Yang Pan, Xiaoting Ren, Shuang Wang, Xin Li, Xianglin Luo, andZongning Yin. Annexin V-conjugated mixed micelles as a potential drug delivery system for targeted thrombolysis. Biomacromolecules 2017, 18, 865-876
2.Lili Wen, Xianxian Zheng, Xinyue Wang, Hairong Lan1 & Zongning Yin. Bilateral effects of excipients on protein stability: Preferential interaction type of excipient and surface aromatic hydrophobicity of protein. Pharm Res. 2017, 34:1378–1390
3.Yongquan Li, Yu Xiao, and Zongning Yin. Enhanced anti-inflammatory efficacy through targeting to macrophages: Synthesis and in vitro evaluation of folate-glycine-celecoxib. AAPS PharmSciTech, 2016, 18(3):729-737
4.Lili Wen, Yan Chen, Jie Liao, Xianxian Zheng, Zongning Yin. Preferential interactions between protein and arginine: Effects of arginine on tertiary conformational and colloidal stability of protein solution. International Journal of Pharmaceutics, 2015, 478:753–761
5.Du, Jinping; Fu, Fazhao; Shi, Xinyue;Yin, Zongning. Controlled release of a model protein drug ovalbumin from thiolated hyaluronic acid matrix. Journal of Drug Delivery Science and Technology. 2015, 30: 74-81
6.Wenyi Zheng, Yongquan Li, Jinping Du, Zongning Yin. Fabrication of Biocompatible and Tumor-Targeting Hyaluronan Nanospheres by a Modified Desolvation Method. Journal of Pharmaceutical Sciences. 2014, 103:1529–1537
7.Zaiyang Xu, Wenyi Zheng, and Zongning Yin. Synthesis and Optimization of a Bifunctional Hyaluronan-Based Camptothecin Prodrug. Arch. Pharm. Chem. Life Sci. 2013, 347, 240–246
8.Zhikui Dong, Wenyi Zheng, Zaiyang Xu, Zongning Yin. Improved Stability and Tumor Targeting of 5-Fluorouracil by Conjugation with Hyaluronan. J. APPL. POLYM. SCI. 2013, 346:1–7
9.Yong Yu, Yiling Lu, Xianmei Zhao, Xiaosi Li, Zongning Yin. Intestinal absorption of raltitrexed and evaluation of the effects ofabsorption enhancers. Pharmazie, 2013, 68:732-743
10.Xiaosi Li, Gonglong Yu, Ke Jin, Zongning Yin. Hyaluronic acid L-cysteine conjugate exhibits controlled-release potential for mucoadhesive drug delivery. Pharmazie, 2012, 67: 224–228
11.Chen-Wen Li, Sheng-Yong Yang, Rui He, Wan-Jun Tao, and Zong-Ning Yin. Development of Quantitative Structure-Property RelationshipModels for Self-Emulsifying Drug Delivery System of 2-Aryl Propionic Acid NSAIDs. Journal of Nanomaterials, 2011, 10.1155
12.Yi-ling Lu, Ben-xia Yang, Zong-ning Yin. Immunotargeting of collagenase on thrombus. International Journal of Nanomedicine, 2010,5:973-982
出版专著
1.药剂学,周四元主编,科学出版社,2017.1,全国规划教材,副主编
2.药物剂型与递药系统,方亮主编,人民卫生出版社,2014.6,全国规划教材,参编
3.药剂学,张志荣主编,高等教育出版社,全国规划教材,2014.4,参编
4.药剂学学习指导与习题集,方亮主编,人民卫生出版社,十二五规划教材,2011.2,参编
5.药剂学学习指导应试指南与习题解析,王东凯主编,中国医药科技出版社,全国高等医药药学类规划教材,2010.5,参编
参考资料
最新修订时间:2023-07-16 14:18
目录
概述
人物经历
社会职务
参考资料