籍晓云，女，汉族，1982年12月生，山西太原人，中共党员，博士学历，南京大学生命科学学院教授、博士生导师。

2001-2005 清华大学 生物科学与技术系 学士 导师：饶子和院士

2005-2010 牛津大学 临床医学系 博士 导师：Prof. Dave Stuart, FRS

2010-2011 牛津大学 结构生物学中心 博士后 导师：Prof. Dave Stuart, FRS

2011-2016 耶鲁大学 分子生物物理与生物化学系 博士后、助理研究员 导师：Prof. Yong Xiong

2016.06- 南京大学 生命科学学院 教授

2017. 获江苏省“双创人才”

病毒感染分子机制研究

针对病毒感染的宿主天然免疫应答机制研究

艾滋病病毒抑制因子的抗病毒分子机制研究

基于结构的合理药物设计

国家自然科学基金面上项目，基于抗病毒蛋白SAMHD1的HIV与宿主细胞间博弈的新分子机制研究

科技部国家重点研发计划，与非编码小RNA 的生成、分泌和吸收相关的新型亚细胞器中的蛋白质机器研究

科技部国家重点研发计划，重大突发动物源性人兽共患病跨种感染与传播机制研究

First Grosvenor Scholar of China Oxford Scholarship, 2005

ORSA (Overseas Research Scholarship Award), 2006

美国国立卫生研究院(NIH)职业发展独立成就奖(NIH K99/R00)，2015

江苏省“双创计划”人才，2017

文章列表：

Li T, Zhao Q, Yang X, Chen C, Yang K, Wu C, Zhang T, Duan Y, Xue X, Mi K, Ji X , Wang Z, Yang H (2018). Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Research . 28, 497–499.

Buzovetsky O*, Tang C*, Knecht K, Antonucci J, Wu L, Ji X #, Xiong Y# (2018). The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nature Communication. 9(1):411(#co-correspondence)

Yu Y, Jin Y, Zhou J, Ruan H, Zhao H, Lu S, Zhang Y, Li D, Ji X , Ruan BH. (2017) Ebselen: Mechanisms of Glutamate Dehydrogenase and Glutaminase Enzyme Inhibition. ACS Chemical Biology . 2017;12(12):3003-11.

Chen X*, Yang K*, Wu C*, Chen C, Hu C, Buzovetsky O, Wang Z, Ji X # , Xiong Y and Yang H# (2016). Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease. Cell Res earch 26(11): 1260-1263.(#co-correspondence)

Antonucci J, St. Gelais C, de Silva S, YountJS, Tang C, Ji X , Shepard C, Xiong Y, Kim B, Wu L. (2016) SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity. Nature Medicine 22(10):1072-4

Tian H*, Ji X *, Yang X*, Zhang Z, Lu Z, Yang K, Chen C, Zhao Q, Chi H, Mu Z, Xie W, Wang Z, Lou H, Yang H, Rao Z. (2016) Structural basis of Zika virus helicase in recognizingitssubstrates. Protein & Cell. 2016:1-9. (*equal contribution)

Tian H*, Ji X*, Yang X*, Xie W, Yang K, Chen C, Wu C, Chi H, Mu Z, Wang Z, Yang H. (2016) The crystal structure of Zika virus helicase: basis for antiviral drug design. Protein & Cell . 2016:1-5. (*equal contribution)

Tang C, Ji X , Wu L, Xiong Y. (2015) Impaired dNTPase Activity of SAMHD1 by Phosphomimetic Mutation of T592.Journal of Biological Chemistry 290(44):26352-9.

Ji X , Axford D, Owen R, Evans G, Ginn H, Sutton G, Stuart DI (2015) Polyhedra structures and the evolution of the insect viruses. Journal of Structural Biology 192(1):88-99.

Ji X , Xiong Y (2015) Two Tales (Tails) of SAMHD1 Destruction by Vpx. Cell host & microbe 17 (4): 425–427

Ginn HM, Messerschmidt M, Ji X , Zhang H, Axford D, Gildea RJ, Winter G, Brewster AS, Hattne J, Wagner A, Grimes JM, Evans G, Sauter NK, Sutton G, Stuart DI (2015) Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nature Communication 6:6435

Ji X *, Tang C*, Zhao Q, Wang W, and Xiong Y (2014) Structural basis of Cellular dNTP regulation by SAMHD1.Proceedings of the National Academy of Sciences 111(41):E4305-E4314 (*equal contribution)

Axford D, Ji X , Stuart DI, Sutton G (2014) In cellulo structure determination of a novel cypoviruspolyhedrin. ActaCrystallographica Section D 70(5):1435-1441.

Ji X * , Wu Y*, Yan J*, Mehrens J, Yang H, DeLucia M, Hao C, Gronenborn AM, Skowronski J, Ahn J, Xiong Y (2013) Mechanism of allosteric activation of SAMHD1 by dGTP. Nature structural & molecular biology 20: 1304-1309 (*equal contribution)

Yang H*, Ji X *, Zhao G, Ning J, Zhao Q, Aiken C, Gronenborn AM, Zhang P, Xiong Y (2012) Structural insight into HIV-1 capsid recognition by rhesus TRIM5α. Proceedings of the National Academy of Sciences 109: 18372-18377 (*equal contribution)

Ji X , Sutton G, Evans G, Axford D, Owen R, Stuart DI (2010) Howbaculovirus polyhedra fit square pegs into round holes to robustly package viruses. EMBO Journal 29(2): 505-514